{"product_id":"igf-des","title":"IGF DES","description":"\u003cp\u003eDES(1-3) IGF-1 DESCRIPTION\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProtein DES(1-3) IGF-1 is a truncated version of peptide hormone IGF-1 (insulin-like growth factor 1) in which the tripeptide Gly-Pro-Glu is absent from the N-terminus end of the protein. In other words, DES(1-3) IGF-1 lacks the first 3 amino acids at the N-terminus of insulin-like growth factor 1, and consists from total of 67 amino acids, relative to the 70 amino acids of IGF-1.\u003c\/p\u003e\n\u003cp\u003eIt is naturally occurring endogenous hormone in human and mammals, that has been found in the human brain, cow colostrum, and pig uterine tissue. The amino acid sequence of DES(1-3) IGF-1 is TLCGAELVDA LQFVCGDRGF YFNKPTGYGS SSRRAPQTGI VDECCFRSCD LRRLEMYCAP LKPAKSA.\u003c\/p\u003e\n\u003cp\u003eCLINICAL TRIALS AND DES(1-3) IGF-1 RESULTS\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eScientific research and clinical trials have shown, that DES(1-3) IGF-1 binds with high-affinity to IGF-1 receptor. And thanks to its a much reduced binding to IGF-binding proteins, caused by the absence of the glutamate at position 3 (tripeptide Gly-Pro-Glu at the N-terminus) is even 10-fold more potent than regular IGF-1 in stimulating hypertrophy and proliferation of cells!\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eClinical opportunities for DES(1-3) IGF-1 have not yet been very evaluated, but could apply in catabolic states (using the peptide to induce anabolism in catabolic conditions such as muscular dystrophy) as well as for the treatment of inflammatory bowel diseases. IGF-1 has a strong ability to maintain and build muscle, especially DES(1-3) IGF-1 form. In addition to a direct anabolic effect on skeletal muscle, the production of more IGF-I is also capable of stimulating the proliferation and differentiation of muscle stem cells (satellite cells) – real growth of new muscle cells, and IGF-1 is the only hormone that can do this. DES(1-3) IGF-1 is also promising candidate for treat of a number of neurological diseases.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eSCIENTIFICALLY INVESTIGATED POSSIBLE BENEFITS OF DES(1-3) IGF-1\u003c\/p\u003e\n\u003cp\u003eOverall regeneration of the whole body (incl. internal organs), increased cellular repair\u003c\/p\u003e\n\u003cp\u003eAnti-aging effects, rejuvenation and the ability to slow-down the aging\u003c\/p\u003e\n\u003cp\u003eIncreased collagen production, healthier skin, helping to smooth out wrinkles\u003c\/p\u003e\n\u003cp\u003eStrong anabolic effect \/ promoting muscle growth, strength and performance\u003c\/p\u003e\n\u003cp\u003eAbility to induce muscle hyperplasia – the growth of new muscle cells\u003c\/p\u003e\n\u003cp\u003eStrong anti-catabolic effect \/ protection against muscle wasting\u003c\/p\u003e\n\u003cp\u003eIncreased bone mineral content \/ greater bone mineral density\u003c\/p\u003e\n\u003cp\u003eImproved cognitive functions, improves learning and memory\u003c\/p\u003e\n\u003cp\u003ePromotes regeneration of the nervous system and brain health\u003c\/p\u003e\n\u003cp\u003eMay reduce risk of heart \u0026amp; cardio-vascular diseases\u003c\/p\u003e\n\u003cp\u003eStrengthened immune system\u003c\/p\u003e\n\u003cp\u003eAnti-inflammatory effects\u003c\/p\u003e\n\u003cp\u003eImproved gut health\u003c\/p\u003e\n\u003cp\u003eDES(1-3) IGF-1 POSSIBLE SIDE-EFFECTS\u003c\/p\u003e\n\u003cp\u003ePossible correlation insulin-like growth factor 1 to certain forms of cancer development (however, performed studies are often unclear, and\u003c\/p\u003e\n\u003cp\u003eoften with conflicting or very different results)\u003c\/p\u003e\n\u003cp\u003eRisk for diabetes (performed studies are often unclear)\u003c\/p\u003e\n\u003cp\u003eLow blood sugar\u003c\/p\u003e\n\u003cp\u003eJoint pain\u003c\/p\u003e\n\u003cp\u003eNausea\u003c\/p\u003e\n\u003cp\u003eAcne\u003c\/p\u003e","brand":"Pharmaco.shop UAE ","offers":[{"title":"Default Title","offer_id":52745490039114,"sku":null,"price":640.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0757\/2707\/7706\/files\/rn-image_picker_lib_temp_e5588586-bc3b-4dae-b7bc-8f38eaf9ca17.jpg?v=1757323953","url":"https:\/\/www.pharmaco.shop\/ru\/products\/igf-des","provider":"Pharmaco.shop UAE ","version":"1.0","type":"link"}